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There is an increasing number of buildings that require informed decisions to be made about their continued safety and serviceability. Although social and economic issues are often all-important influences, the technical issues nevertheless need to be addressed objectively, efficiently and reliably. This book shows how monitoring the physical behaviour of a structure can assist the engineer to meet these conditions when making an assessment. The book is aimed primarily at the practising engineer charged with making recommendations in respect of safety and serviceability. By the same token, it will be of value to the client specifying a brief for assessment or evaluating the report of an investigation which involves monitoring. The book will also be one of reference for those engaged in research involving monitoring, and an aid to the advanced student who needs to understand better the full-scale performance in service of building structures. The need to assess safety and serviceability may arise for a variety of reasons, ranging from problems developing in service to change of use or the introduction of innovative features at the design stage. These reasons are explored in the first chapter which establishes a philosophy by which the assessing engineer can determine appropriate courses of action. Observations and measurements which do not address the real issues are worthless but too much information which cannot be effectively digested and interpreted is also not useful.

Randomized clinical trials are the gold standard for establishing many clinical practice guidelines and are central to evidence based medicine. Obtaining the best evidence through clinical trials must be done within the boundaries of rigorous science and ethical principles. One fundamental principle is that trials should not continue longer than necessary to reach their objectives. Therefore, trials must be monitored for recruitment progress, quality of data, adherence to patient care or prevention standards, and early evidence of benefit or harm. Frequently, a group of external experts, independent from the investigators and trial sponsor, is charged with this monitoring responsibility, especially for safety and early benefit. This group is referred to by various names, such as a data monitoring committee or a data and safety monitoring board. This book, through a series of case studies presented by many distinguished clinical trial experts, illustrates the complexity of this monitoring process. The editors provide an overview of the process and a summary of a multitude of the lessons learned from the cases presented.§This book should be useful to anyone serving on a data and safety monitoring board, or planning to do so, for colleagues in academia, industry and governmental agencies, and for teaching students in biostatistics, epidemiology, clinical trials and medical ethics. No other text has as extensive a collection of cases which provide insight into the many issues, often conflicting, that must be examined before recommendations to continue or discontinue a trial can be made. While depth in statistical methods is not required, some familiarity with statistical design and analysis issues in clinical trials is helpful. The cases cover trials which were terminated early for convincing evidence of benefit, or for harmful effects. Cases with complex issues are also included. This series of cases should provide broad background information for potential monitoring committee members and better prepare them for the challenges that may exist in the trials for which they are responsible. §"This book is a must-read for individuals serving on or supporting data monitoring committees as well as statisticians and other disciplines involved in the design and analysis of clinical trials with interim monitoring." Journal of Biopharmaceutical Sciences, Issue 6, 2006

This proceedings book presents a discussion by leading scientists and specialists of the latest scientific results, developed methods, technologies and technical means of research and pilot work in the field of geosciences and environmental management. An important task is to familiarize young specialists, teachers, graduate students and students with the current state and the latest world achievements in this field of knowledge. Currently, there is a rapid and significant climate change, which manifests itself not only in global warming, but also in noticeable changes in other atmospheric and climatic characteristics among others.

This book covers the up-to-date advancement of respiratory monitoring in ventilation support as well as detecting the physiological responses to therapeutic interventions to avoid complications. Mechanical ventilation nowadays remains the cornerstone in life saving in critically ill patients with and without respiratory failure. However, conclusive evidences show that mechanical ventilation can also cause lung damage, specifically, in terms of ventilator-induced lung injury.Respiratory monitoring encloses a series of physiological and pathophysiological measurements, from basic gas exchange and ventilator wave forms to more sophisticated diaphragm function and lung volume assessments. The progress of respiratory monitoring has always been accompanied by advances in technology. However, how to properly conduct the procedures and correctly interpret the data requires clear definition.The book introduces respiratory monitoring techniques and data analysis, including gas exchange, respiratory mechanics, thoracic imaging, lung volume measurement, and extra-vascular lung water measurement in the initial part. How to interpret the acquired and derived parameters and to illustrate their clinical applications is presented thoroughly. In the following part, the applications of respiratory monitoring in specific diseases and conditions is introduced, including acute respiratory distress syndrome, obstructive pulmonary diseases, patient-ventilator asynchrony, non-invasive ventilation, brain injury with increased intracranial pressure, ventilator-induced diaphragm dysfunction, and weaning from mechanical ventilation.This book is intended primarily for ICU physicians and other practitioners including respiratory therapists, ICU nurses and trainees who come into contact with patients under mechanical ventilation. This book also provides guidance for clinical researchers who take part in respiratory and mechanical ventilation researches.

This book equips the intraoperative monitoring provider (both technologist and physician) with details of commonly monitored surgical procedures of the spine. This knowledge better allows the monitorist to identify critical phases of the surgery and correlate those with neuroanatomical and functional risk at each phase. Chapters are authored by a surgeon and neurophysiologist, with the surgeon contributing procedural content and the neurophysiologist contributing information on how the monitoring integrates within the context of the procedure. It is the first book that incorporates content about the surgical procedure directly with the intraoperative monitoring plan for the surgery.

Wearable Systems Based Gait Monitoring and Analysis provides a thorough overview of wearable gait monitoring techniques and their use in health analysis. The text starts with an examination of the relationship between the human body's physical condition and gait, and then introduces and explains nine mainstream sensing mechanisms, including piezoresistive, resistive, capacitive, piezoelectric, inductive, optical, air pressure, EMG and IMU-based architectures. Gait sensor design considerations in terms of geometry and deployment are also introduced. Diverse processing algorithms for manipulating sensors outputs to transform raw data to understandable gait features are discussed. Furthermore, gait analysis-based health monitoring demonstrations are given at the end of this book, including both medical and occupational applications. The book will enable students of biomedical engineering, electrical engineering, signal processing, and ergonomics and practitioners to understand the medical and occupational applications of engineering-based gait analysis and falling injury prevention methods.

Soft sensors are inferential estimators, drawing conclusions from process observations when hardware sensors are unavailable or unsuitable; they have an important auxiliary role in sensor validation when performance declines through senescence or fault accumulation.§The non-linear behaviour exhibited by many industrial processes can be usefully modelled with the techniques of computational intelligence: neural networks; fuzzy systems and nonlinear partial least squares.§Soft Sensors for Monitoring and Control of Industrial Processes underlines the real usefulness of each approach and the sensitivity of the individual steps in soft-sensor design to the choice of one or the other. Design paths are suggested and readers shown how to evaluate the effects of their choices. All the case studies reported, resulting from collaborations between the authors and a number of industrial partners, raised challenging soft-sensor-design problems. The applications of soft sensors presented in this volume are designed to cope with the whole range from measuring system backup and what-if analysis through real-time prediction for plant control to sensor diagnosis and validation. Some of the soft sensors developed here are implemented on-line at industrial plants.§Features:§soft-sensor design;§advice on data selection and choice of model structure;§model validation;§strategies for the improvement of soft-sensor performance;§uses of soft sensors in fault detection and sensor validation;§soft sensors in use in industrial applications such as a debutanizer column and a sulfur recovery unit.§This monograph guides interested readers researchers, graduate students and industrial process technologists through the design of their own soft sensors. It is self-contained with full references and appraisal of existing literature and data sets for some of the case studies can be downloaded from springer.com.This book reviews current design paths for soft sensors, and guides readers in evaluating different choices. The book presents case studies resulting from collaborations between the authors and industrial partners. The solutions presented, some of which are implemented on-line in industrial plants, are designed to cope with a wide range of applications from measuring system backup and what-if analysis through real-time prediction for plant control to sensor diagnosis and validation.Soft sensors are inferential estimators, drawing conclusions from process observations when hardware sensors are unavailable or unsuitable; they have an important auxiliary role in sensor validation when performance declines through senescence or fault accumulation.§The non-linear behaviour exhibited by many industrial processes can be usefully modelled with the techniques of computational intelligence: neural networks; fuzzy systems and nonlinear partial least squares.§Soft Sensors for Monitoring and Control of Industrial Processes underlines the real usefulness of each approach and the sensitivity of the individual steps in soft-sensor design to the choice of one or the other. Design paths are suggested and readers shown how to evaluate the effects of their choices. All the case studies reported, resulting from collaborations between the authors and a number of industrial partners, raised challenging soft-sensor-design problems. The applications of soft sensors presented in this volume are designed to cope with the whole range from measuring system backup and what-if analysis through real-time prediction for plant control to sensor diagnosis and validation. Some of the soft sensors developed here are implemented on-line at industrial plants.§Features: soft-sensor design; advice on data selection and choice of model structure; model validation; strategies for the improvement of soft-sensor performance; uses of soft sensors in fault detection and sensor validation; soft sensors in use in industrial applications such as a debutanizer column and a sulfur recovery unit.§This monograph guides interested readers researchers, graduate students and industrial process technologists through the design of their own soft sensors. It is self-contained with full references and appraisal of existing literature and data sets for some of the case studies can be downloaded from springer.com. §Advances in Industrial Control aims to report and encourage the transfer of technology in control engineering. The rapid development of control technology has an impact on all areas of the control discipline. The series offers an opportunity for researchers to present an extended exposition of new work in all aspects of industrial control.

This book describes the§pathophysiological significance of the hemodynamic monitoring parameters§available to the clinician and their role in providing reliable and§reproducible information on the cardiocirculatory status of a patient in shock.§It is explained how measurements of these parameters enable the intensivist to§understand the patient's condition and to make more informed treatment§decisions in order to optimize the hemodynamic status and improve the§prognosis. Full guidance is provided on measurement of intravascular blood§pressures, cardiac output, and derived variables. Methods of cardiac output§determination based on the classical pulmonary thermodilution, transpulmonary§thermodilution, echocardiography, and Doppler techniques are reviewed. Techniques§based on calibrated and non-calibrated pulse contour analysis are discussed,§with attention to their limitations. Furthermore, the dynamic indices of fluid§responsiveness, their clinical applications, and issues related to their use§are addressed. Care is also taken to explain the physiological concepts§underlying various devices used by anesthesiologists and intensivists.§§

This book describes how to monitor and optimize cardiovascular dynamics using advanced hemodynamic monitoring in perioperative and intensive care medicine. The book outlines basic skills of hemodynamic monitoring, different techniques including invasive, minimally invasive, and non-invasive methods, and algorithms and treatment strategies for perioperative goal-directed hemodynamic therapy in different groups of surgical patients. Thus, the book reflects current diagnostic and therapeutic approaches in perioperative and intensive care medicine. All sections of this book have a learning-oriented style and are illustrated with tables and figures summarizing the main content. The volume is addressed both to specialists and residents using advanced hemodynamic monitoring; it reflects indications and limitations of current monitoring tools and discuss therapeutic strategies. It also helps readers to integrate new knowledge on monitoring of cardiovascular dynamics into clinical practice.

Reliable methods for monitoring and assessing soil quality are a prerequisite for successful soil bioremediation projects. The fifth volume of Soil Biology presents detailed descriptions of selected methods for evaluating, monitoring and assessing bioremediation treatments of soils contaminated with organic pollutants or heavy metals.§Traditional soil investigation techniques, including chemical, physical and microbiological methods, are complemented by the most suitable modern methods, such as the use of bioreporter technology, immunological, ecotoxicological or molecular assays. Feasibility studies for bioremediation treatments complete the manual. Easy-to-follow protocols with step-by-step procedures, lists of the required equipment and reagents as well as notes on the evaluation and quality control allow immediate application. Short introductions to the principles and objectives help to assess the field of application of each procedure.

This book provides comprehensive information on continuous glucose monitoring (CGM). The first section focuses on the fundamentals of CGM technology, including the principles of CGM, accuracy assessment, operation procedure, management processes, the pi

This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today's intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands.The book is divided into three parts: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting.The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.

The third edition of this classic text again provides practical, comprehensive coverage of the anatomical and physiological basis for intraoperative neurophysiological monitoring. Written by a leading authority in the field, Dr. Agge Moller has updated this important title to again offer all the leading-edge knowledge needed to perform electrophysiological recordings in the operating room, to interpret the results, and to present the results to the surgeon. The field known as "intraoperative monitoring" has expanded rapidly to cover other uses of neurophysiology and electrophysiologic recordings during surgical operations that affect the brain, spinal cord, and other parts of the nervous system. These new areas are covered in this new edition. To better represent the content of the book and the field as it now stands, many of the chapters have been revised with new material added. While the general organization of the book is maintained, chapters such as monitoring of motor systems have been revised and extended with new material, including a more detailed description of the anatomy and physiology of motor systems and new information about intraoperative monitoring.

In recent decades, the advances in and consolidation of Intraoperative Neurophysiological Monitoring (IOM) in several highly complex surgical areas have been undeniable.Currently all modalities of neurophysiological tests (SSEP, MEP, EMG, PEATC, VEP, BRAIN MAPPING, ETC) are performed in the operating room, where they are used to provide trans operative information on the patient's neurological status in real time (monitoring), and to identify neural structures which are at immediate risk (mapping). With the inarguably positive impact of IOM on surgical outcomes, there is an increasing interest in reliable, technically focused literature. This volume provides cutting-edge information in the field of IOM, and highlights new neurophysiological tools being used in various surgeries.The book's initial sections cover a range of topics, including an anatomical overview, electrical safety, and detailed technical descriptions of the neurophysiological tests used in IOM. The subsequent sections address e.g. the brain, brainstem, spinal cord, vascular and peripheral nerves, epilepsy, head and neck, movement disorders and special topics.Some chapters are accompanied by videos of surgeries and IOM so that the reader will have the real sensation of having been in the operating room and will gain an overview of the key steps.Written by experts in the field of IOM, the book offers a valuable resource for both experienced and early-career neurophysiologists, neurosurgeons, vascular and orthopedic surgeons, and surgeons involved with pelvic procedures. Further, its goal is to provide a real rapport, never before attained, between neurophysiologists and surgeons with a sole focus: excellence in terms of the final outcome.

This book offers a comprehensive overview of the basic physiology of the cardiac and pulmonary systems, tools for cardiopulmonary monitoring, and related issues in the management of specific conditions. The volume is divided into three main parts. The first part examines the functional basis of normal and abnormal physiology, organized into cardiac and pulmonary units and followed by a "combined" interactive component. The next section discusses cardiopulmonary monitoring tools and variables and is also divided into cardiac (e.g, echocardiography, heart rate, cardiac output), pulmonary (e.g, lung volume, pleural pressure, electrical impedance tomography), and combined tools such as radiology/MRI and tissue perfusion tests. The third section concerns the management and application of specific clinical problems such as pulmonary hypertension, cardiac shunts, cardiogenic shock, and ECMO with an emphasis on the physiological basics. Cardiopulmonary Monitoring: Basic Physiology, Tools, and Bedside Management for the Critically Ill is an essential resource for physicians, residents, fellows, medical students, and researchers in cardiology, critical care, emergency medicine, anesthesiology, and radiology.

This book discusses the architecture of modern automated systems for spectrum monitoring including automation components: technical means for spectrum monitoring, special software and engineering infrastructure.

The harmful impacts of pollution on atmospheric, terrestrial and aquatic environments can cause extreme temperature changes, clean water shortage, and increase toxicity. This book studies environmental pollution impacts, from the mechanism of toxic nanoparticles on the molecular level to the detection of trace gas on the satellite perspective. It presents recent developments in advanced monitoring techniques, efficient process technologies and health impact assessment tools, from environmental scientists of diversified fields. The three sections highlight important aspects of emerging monitoring technologies in Atmospheric Environment, Contaminants Control Process and Environmental Toxicity Assessment. Observational tools presented in the first section range from in-situ analytical to digital techniques for atmospheric monitoring. Highlighted in the second section is the recently developed water quality monitoring system for lake stratification and membrane technologies for detection and removal of contaminants. Lastly, toxicity mechanisms of endocrine disruptors and nanoparticles are highlighted on the third section, with important new discoveries. The major topics addressed are: atmospheric environmental monitoring, including monitoring and modeling of trace air pollutants, contaminants control process monitoring, environmental toxicity monitoring and assessments, biological and chemical monitoring for environmental toxicity, monitoring technology for desalination water quality and toxicity measurement of desalted and concentrated water.

Continuous EEG monitoring is an important tool for assessing brain function and allows clinicians to identify malignant EEG patterns quickly and provide more effective care. The revised and updated second edition of Handbook of ICU EEG Monitoring distills the wide range of technical and clinical..