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Breast cancer remains the leading cause of cancer in women, which makes accurate diagnoses on core needle biopsy (CNB) specimens of vital importance in staging and guiding therapy decisions for patients.   The first edition of this multi-authored text written by leaders in the field from major academic medical centers provided a comprehensive guide on diagnostic breast pathology in the core biopsy setting.  In addition to in-depth coverage of benign and malignant entities encountered in breast core biopsies, the book provided additional resources to improve diagnostic accuracy such as pattern-based approaches to evaluation, mimickers of breast lesions arising in extra-mammary sites, and pitfalls specific to small tissue samples.     In recent years, there have been several notable developments in the field of breast pathology including revisions in AJCC breast cancer staging, updated guidelines in the testing and reporting of ER, PR, and HER2, as well as implementation of immunotherapy and companion biomarker testing.  In addition, several key updates were included in the most recent edition of the WHO Classification of Breast Tumours (2020). In addition to updates specific to individual breast entities, the second edition will detail updates regarding biomarker testing in the primary and metastatic setting, and incorporate newly defined entities and updated definitions of rare tumors in alignment with the WHO Classification of Breast Tumours (2020).  Furthermore, this edition will address the role of CNB in companion biomarker testing for eligibility for immunotherapy in the context of advanced triple-negative breast carcinoma. Written by leaders in the field and edited by expert breast pathologists, The Second Edition of Comprehensive Guide to Core Needle Biopsies of the Breast is the definitive reference on breast core needle biopsies for practicing pathologists, pathology trainees, oncologists and clinicians of patients with breast disease.

This book provides a practical, step-by-step guidance on modern workhorse flaps for plastic and reconstructive surgeons in training or in their early career. The 50 chapters cover everything from surgical fundamentals to preconditions of microsurgical techniques, but also covers pre-operative planning, steps of microsurgical dissection and management of complications in a straightforward, explanatory style, and are supplemented by over 600 clinical illustrations and cadaveric images. Further videos demonstrations with pertinent steps in flap dissection, anatomical nomenclature and long-term outcomes are also demonstrated. For each flap a detailed discussion of key papers concerning its origin, pitfalls, technical refinements and tips for success are also included. Specific notes on common reconstructive challenges and complications, this book offers a valuable reference tool and would be unquestionably an integral reference guide for every surgeon interested in reconstructive microsurgical techniques, especially during their early microsurgical career.

This book shows how SAP s business suite supports logistic end-to-end processes, exploring relevant functionality, system and application integration to outline closed-loop supply chain processes in Inventory Management, Warehousing, Transportation.

Oracle Core: Essential Internals for DBAs and Developers by Jonathan Lewis provides just the essential information about Oracle Database internals that every database administrator needs for troubleshooting no more, no less. §Oracle Database seems complex on the surface. However, its extensive feature set is really built upon upon a core infrastructure resulting from sound architectural decisions made very early on that have stood the test of time. This core infrastructure manages transactions and the ability to commit and roll back changes, protects the integrity of the database, enables backup and recovery, and allows for scalability to thousands of users all accessing the same data. §Most performance, backup, and recovery problems that database administrators face on a daily basis can easily be identified through understanding the essential core of Oracle Database architecture that Lewis describes in this book. §Provides proven content from a world-renowned performance and troubleshooting expert Emphasizes the significance of internals knowledge to rapid identification of database performance problems Covers the core essentials and does not waste your time with esoterica